The ability to connect to any device anywhere is essential to modern business. Being able to retrieve data and manage equipment over the network saves time and reduces costs. However, different devices require different connectivity options. One of the most popular options implemented on smart devices and peripherals is USB — providing a low cost, flexible interface for intelligent communication with complex devices. Demand for USB connectivity has grown accordingly, leading to new problems to solve. In this paper we discuss some of these challenges and how Digi AnywhereUSB® Plus solves them.